Squalene Market (2026 - 2033) Size, Share & Trends Analysis Report By Source (Animal, Plants, Synthetic), By End Use (Pharmaceuticals, Food & Beverages, Nutraceuticals), By Region (North America, Europe, Asia Pacific, Latin America, MEA), And Segment Forecasts

Squalene Market Summary

The global squalene market size was estimated at USD 183.7 million in 2025 and is projected to reach USD 419.5 million by 2033, growing at a CAGR of 10.9% from 2026 to 2033. This growth is primarily driven by increasing demand for natural and bio-based ingredients in cosmetics and personal care formulations, where squalene is widely used for its moisturizing and antioxidant properties.

Rising consumer preference for plant-derived ingredients, particularly olive and amaranth-based squalene, is also supporting market expansion. In addition, the growing adoption of squalene in pharmaceutical applications, including vaccine adjuvants and drug delivery systems, is further contributing to demand.

The squalene market is experiencing the rapid growth due to demand for cosmetics and personal care, particularly in skincare and anti-aging products. Squalene is valued for its ability to improve skin hydration, restore elasticity, and enhance the absorption of active ingredients. As consumers increasingly prioritize natural, sustainable, and functional cosmetic ingredients, manufacturers are incorporating squalene into serums, moisturizers, sunscreens, and hair care products.

Another major driver is the expanding pharmaceutical and biotechnology sector, where squalene plays an important role in vaccine formulations and advanced drug delivery systems. It is commonly used as an adjuvant to enhance immune response in vaccines, which has increased its relevance in global immunization programs. Continued research in lipid-based drug delivery technologies and the growing demand for effective vaccine components are expected to further drive market growth.

Market Concentration & Characteristics

The global squalene market is moderately consolidated, with a limited number of manufacturers controlling a significant share of production and supply. Major producers focus on plant-derived squalene extraction and purification technologies to meet rising demand from cosmetics and pharmaceutical industries. Companies are investing in sustainable sourcing and improved extraction methods to enhance product quality and supply stability/ 

Competitive dynamics in the market are influenced by raw material availability, regulatory compliance, and sustainability considerations. Producers that can ensure consistent supply of high-purity squalene while addressing environmental concerns are well positioned in the market. Strategic partnerships with cosmetic and pharmaceutical companies also play a key role in maintaining competitive advantage

Source Insights

The plants segment dominated the market with a revenue share of 82.5%, in 2025. largely due to growing consumer preference for sustainable and cruelty-free ingredients. Plant-derived squalene, particularly from olive oil, amaranth seeds, and rice bran, is widely used in cosmetic formulations due to its high purity and compatibility with skin. Increasing regulatory restrictions on shark-derived ingredients have further accelerated the shift toward plant-based sources.

Animal segment is expected to grow significantly with a CAGR of 10.7% during the forecast period. This growth is primarily due to the continued use of shark liver oil as a concentrated source of squalene for pharmaceutical applications, particularly in vaccine adjuvants. Certain medical and research applications still rely on animal-derived squalene due to its high yield and established supply chains. However, ethical concerns and environmental sustainability issues are encouraging a gradual transition toward alternative sources.

End Use Insights

Personal care & cosmetics dominated the market with a revenue share of 70.1% in 2025. This segment benefits from widespread use of squalene as an emollient and antioxidant in skincare products, including moisturizers, anti-aging creams, and serums. Its ability to mimic natural skin lipids makes it highly effective in improving hydration and skin barrier function. Increasing consumer awareness of skin health and demand for premium skincare products are driving its adoption across global cosmetic brands.

Pharmaceuticals is expected to grow fastest with a CAGR of 11.1% during the forecast period. This growth is driven by increasing use of squalene in vaccine adjuvants and lipid-based drug delivery systems. Pharmaceutical manufacturers are exploring its potential to enhance immune response and improve therapeutic efficacy. Ongoing vaccine development programs and advancements in biotechnology are expected to support sustained demand for squalene in the pharmaceutical sector.

Regional Insights

Europe squalene market dominated the global market with a revenue share of 32.7% in 2025. This growth is driven by strong demand from the region’s well-established cosmetics and personal care industry. The presence of premium skincare brands and increasing consumer preference for natural ingredients support market growth. Regulatory emphasis on sustainable and cruelty-free sourcing further accelerates the adoption of plant-derived squalene.

Squalene market in Germany plays an important role in the European market due to its advanced pharmaceutical and cosmetic manufacturing industries. The country emphasizes sustainable ingredient sourcing and high-quality cosmetic formulations. Strong research capabilities in biotechnology further support squalene demand in pharmaceutical applications.

Asia Pacific Squalene Market Trends

Asia Pacific is one of the fastest-growing markets due to expanding cosmetics manufacturing and rising consumer spending on skincare products. Countries such as China, Japan, and South Korea are key demand centers for squalene-based formulations. Increasing pharmaceutical production and vaccine manufacturing activities also contribute to regional market growth.

Squalene market in China is growing rapidly due to rapid expansion in cosmetics manufacturing and pharmaceutical production. Rising consumer demand for skincare and beauty products is driving the adoption of squalene-based formulations. Government support for biotechnology and vaccine manufacturing further strengthens market growth.

North America Squalene Market Trends

North America accounts for a significant share of the squalene market, supported by strong demand from both cosmetic and pharmaceutical industries. The region benefits from advanced biotechnology research and high adoption of premium skincare products. Growing interest in natural cosmetic ingredients continues to drive product innovation.

U.S. Squalene Market Trends

The U.S. market is driven by strong demand for premium skincare products and advanced pharmaceutical research. Squalene is widely used in cosmetic formulations and vaccine adjuvants developed by biotechnology companies. High consumer awareness regarding natural and sustainable ingredients supports market expansion.

Latin America Squalene Market Trends

Latin America is experiencing gradual growth in the squalene market, driven by expanding personal care product consumption and improving economic conditions. Increasing awareness of skincare and natural ingredient-based cosmetics supports demand. Brazil and Mexico represent key markets within the region.

Middle East And Africa Squalene Market Trends

The Middle East & Africa market is developing steadily, supported by rising demand for cosmetic and pharmaceutical products. Increasing urbanization and growing disposable incomes are encouraging the adoption of premium personal care products. However, limited local production capacity means the region relies largely on imports.

Key Squalene Company Insights

The global squalene market is characterized by the presence of several established ingredient manufacturers and specialty chemical companies involved in the production and supply of plant- and animal-derived squalene.

Companies are investing in advanced extraction and purification technologies to improve product quality and ensure consistent supply for cosmetics and pharmaceutical applications. Strategic partnerships with personal care and biotechnology companies are also being pursued to strengthen market presence and expand application development. Additionally, manufacturers are prioritizing sustainable sourcing and supply chain optimization to meet increasing demand for natural and ethically produced squalene

Company Overview:

The company offers its products to various markets such as agriculture, food, pharmaceutical, fragrances, water treatment, lubricants, wood & furniture, textiles, electronics, automotive, beauty & personal care, among others. The company also offers crop protection, adjuvants, chemical biostimulants, seed enhancement, specialty additives for agricultural films, and animal health products. It has 30 manufacturing sites globally and has several sales offices and laboratories across the globe.

Recent Developments

• In October 2023, Evonik Industries AG announced the launch of GMP-quality, plant-based squalene, now available for commercial and clinical use. This is the GMP-grade, GMP-certified squalene derived from amaranth oil, an adjuvant for use in parenteral dosage forms.

• In May 2023, Amyris announced its partnership with Croda International Plc. to supply pharmaceutical-grade squalene as an adjuvant to boost the immune response.

Squalene Market Report Scope

Global Squalene Market Report Segmentation

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, Grand View Research has segmented the global squalene market report based on source, end use, and region.

• Source Outlook (Volume, Kilotons; Revenue, USD Million, 2021 - 2033)

  • Animal

    • Shark Liver Oil

    • Other Animals

  • Plants

    • Amaranth Oil

    • Olive Oil

    • Rice Barn Oil

    • Other Plants

  • Synthetic

• End Use Outlook (Volume, Kilotons; Revenue, USD Million, 2021 - 2033)

  • Pharmaceuticals

  • Food & Beverages

  • Nutraceuticals

  • Personal Care & Cosmetics

  • Other End Use

• Regional Outlook (Volume, Kilotons; Revenue, USD Million, 2021 - 2033)

  • North America

    • U.S.

    • Canada

    • Mexico

  • Europe

    • Germany

    • France

    • Spain

    • Italy

    • UK

  • Asia Pacific

    • China

    • India

    • Japan

    • South Korea

    • Vietnam

    • Thailand

    • Indonesia

  • Latin America

    • Brazil

    • Argentina

  • Middle East & Africa

    • Saudi Arabia

    • South Africa